I am on Win7/64. I got the USB blaster from here. I got the JTAG header from here. I wound up installing the an older version of Quartus II software (7.1), but frankly I think all you need is the Quartus II programmer and the windows drivers. Next I downloaded the Altera USB driver here, and installed the drivers and the device says working. But when I open the Quartus II programmer, it will not find the device. Keeps saying Unable to scan device chain. Basically the error is no device detected. I have the Genesis on, with the ED inserted. However, I saw in another post a good hint. I removed the pins from the header's plastic holder and put them each into the JTAG cable. Bingo. Guess they weren't long enough before. Easily upgraded firmware on 2.1 MD-ED to 12!